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Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations PDF available through Get Fulltext Research

Hucke, Anna Park, Ga Young Bauer, Oliver B. Beyer, Georg Köppen, Christina Zeeh, Dorothea Wehe, Christoph A. Sperling, Michael Schröter, Rita Kantauskaitè, Marta ...

Published in Frontiers in Chemistry

Cancer treatment with platinum compounds is an important achievement of modern chemotherapy. However, despite the beneficial effects, the clinical impact of these agents is hampered by the development of drug resistance as well as dose-limiting side effects. The efficacy but also side effects of platinum complexes can be mediated by uptake through ...

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