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Contrast Sensitivity With a Subretinal Prosthesis and Implications for Efficient Delivery of Visual Information.

Goetz, Georges Smith, Richard Lei, Xin Galambos, Ludwig Kamins, Theodore Mathieson, Keith Sher, Alexander Palanker, Daniel

Published in Investigative ophthalmology & visual science

To evaluate the contrast sensitivity of a degenerate retina stimulated by a photovoltaic subretinal prosthesis, and assess the impact of low contrast sensitivity on transmission of visual information. We measure ex vivo the full-field contrast sensitivity of healthy rat retina stimulated with white light, and the contrast sensitivity of degenerate ...

Transcriptome Profiling of Developing Murine Lens Through RNA Sequencing.

Khan, Shahid Y Hackett, Sean F Lee, Mei-Chong W Pourmand, Nader Talbot, C Conover Jr Riazuddin, S Amer

Published in Investigative ophthalmology & visual science

Transcriptome is the entire repertoire of transcripts present in a cell at any particular time. We undertook a next-generation whole transcriptome sequencing approach to gain insight into the transcriptional landscape of the developing mouse lens. We ascertained mouse lenses at six developmental time points including two embryonic (E15 and E18) and...

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Contrast Sensitivity With a Subretinal Prosthesis and Implications for Efficient Delivery of Visual Information.

Transcriptome Profiling of Developing Murine Lens Through RNA Sequencing.