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Characterization of pHEMA-based hydrogels that exhibit light-induced bactericidal effect via release of NO PDF available through Get Fulltext Research

Halpenny, Genevieve M. Steinhardt, Rachel C. Okialda, Krystle A. Mascharak, Pradip K.

Published in Journal of Materials Science: Materials in Medicine

A light-activated NO donor, [Mn(PaPy3)(NO)]ClO4 (1a), has been incorporated into HEMA-based polymer hydrogel and the nitrosyl-polymer conjugate materials 1ax · HG and 1ax · HGMB have been characterized. The NO releasing properties and antibacterial capabilities of these materials in conjunction with growth attenuators such as hydrogen peroxide and ...

Design and construction of a silver(I)-loaded cellulose-based wound dressing: trackable and sustained release of silver ...

deBoer, T. R. Chakraborty, I. Mascharak, P. K.

Published in Journal of Materials Science: Materials in Medicine

Although application of silver nitrate and silver sulfadiazine have been shown to be effective in thwarting infections at burn sites, optimization of the delivery of bioactive silver (Ag+) remains as an obstacle due to rapid precipitation and/or insolubility of the silver sources. To circumvent these shortcomings, we have designed a silver(I) compl...

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